Manuel Dujovny Selected Research

Neomycin

12/2004	Perivascular delivery of neomycin inhibits the activation of NF-kappaB and MAPK pathways, and prevents neointimal hyperplasia and stenosis after arterial injury.
6/2004	Differentiation-inducing activity of neomycin in cultured rat glioma cells.
4/2004	Neomycin inhibits glioma cell migration.
10/2003	Antiproliferative action of neomycin is associated with inhibition of cyclin D1 activation in glioma cells.
4/2003	Glioma cell-associated sustained activation of the transcription factor, nuclear factor-kappa B, was inhibited by neomycin.
1/2003	Dual blockade of mitogen-activated protein kinases ERK-1 (p42) and ERK-2 (p44) and cyclic AMP response element binding protein (CREB) by neomycin inhibits glioma cell proliferation.
9/2002	Inhibition of rat glioma growth by neomycin. Preliminary report.
6/2002	Antiproliferative effect of neomycin in glioma cells.

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Manuel Dujovny Research Topics

Disease

7	Neoplasms (Cancer) 12/2004 - 06/2002
7	Glioma (Gliomas) 06/2004 - 06/2002
3	Aneurysm (Aneurysms) 12/2010 - 07/2009
1	Intracranial Aneurysm (Cerebral Aneurysm) 07/2009
1	Hyperplasia 12/2004
1	Inflammation (Inflammations) 12/2004
1	Pathologic Constriction (Stenosis) 12/2004
1	Wounds and Injuries (Trauma) 04/2004
1	Peripheral Nerve Injuries 03/2004
1	Glioblastoma (Glioblastoma Multiforme) 10/2003
1	Congenital Abnormalities (Deformity) 10/2002
1	Fatigue 10/2002

Drug/Important Bio-Agent (IBA)

8	Neomycin FDA LinkGeneric 12/2004 - 06/2002
3	Proteins (Proteins, Gene)FDA Link 12/2004 - 01/2003
2	NF-kappa B (NF-kB)IBA 12/2004 - 04/2003
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2003 - 06/2002
1	Stainless Steel (Steel, Stainless)IBA 12/2010
1	ChromiumIBA 12/2010
1	CobaltIBA 12/2010
1	TitaniumIBA 12/2010
1	PolymersIBA 07/2009
1	Glial Fibrillary Acidic ProteinIBA 06/2004
1	Cyclin D1IBA 10/2003
1	Therapeutic UsesIBA 10/2003
1	Transcription Factors (Transcription Factor)IBA 04/2003
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2003
1	Cyclic AMP (AMP, Cyclic)IBA 01/2003
1	Mitogen-Activated Protein KinasesIBA 01/2003
1	ElementsIBA 01/2003
1	Carrier Proteins (Binding Protein)IBA 01/2003
1	Polyethylene (Polythene)IBA 10/2002

Therapy/Procedure

3	Therapeutics 07/2009 - 09/2002
1	Surgical Instruments (Clip) 12/2010
1	Catheters 07/2009
1	Craniotomy 10/2002